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La PCOS nel maschio? Similitudini e rischi per la sua salute


ABSTRACT
{ITA} Insulino-resistenza e conseguente iperinsulinsmo nella PCOS giocano un ruolo cruciale e nel lungo termine portano a sindrome metabolica. Nella eziopatogenesi della PCOS la componente genetica ha ruolo importante, è ipotizzabile nell’uomo un quadro disendocrino simil-PCOS, con lineamenti fenotipici differenti, ma con caratteristiche biochimiche ed ormonali che mostrano analogie evidenziante in studi su uomini parenti di donne affette da PCOS, studi su uomini con early onet androgenic alopecia (<dei 35 aa), evidenza in disordini metabolici, malattie coronariche e malattie prostatiche. Il riconoscimento di questa ipotetica sindrome potrebbe prevenire complicanze a lungo termine di molte patologie.

{ENG} PCOS is characterized by insulin resistance who plays an important role in the incoming of long-term complications due to metabolic syndrome.
The occurrence of a genetic background in the etiology of PCOS represents the rational basis to postulate the existence of a male PCOS equivalent. Hormonal and metabolic abnormalities have been described in male relatives of women with PCOS: early onset (<35 years) androgenetic alopecia, type II diabetes mellitus, cardiovascular diseases prostatic diseases (BPH, Prostate cancer and prostatitis), these findings support the existence of the male PCOS equivalent. Its acknowledgment would be helpful for the prevention of these long-term complications.


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12° Corso Strategie integrative, neuro-attive, e terapie ormonali in Ginecologia Endocrinologica
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