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Si può prevedere l’età di insorgenza della menopausa?


ABSTRACT
{ITA} L’età alla menopausa, come tutte le variabili biologiche, è distribuita in modo normale, con una mediana che si stabilisce intorno ai 51 anni. Il fattore che più ne condiziona l’insorgenza è la riserva ovarica, che risulta condizionata da diversi fattori sia di tipo genetico che acquisito. L’utilizzo di markers di riserva ovarica sia di tipo ecografico che ormonale sono in grado di fornirci in modo indiretto una misura molto attendibile della riserva ovarica. I markers di riserva ovarica sono stati utilizzati in modelli matematici per la predizione dell’età alla menopausa che ha conseguenze cliniche molto importanti sia per la salute globale della donna sia per la prognosi riproduttiva.

{ENG} Age at menopause, like all biological variables, has a normal distribution with a median of 51 years. Her main determinant is ovarian reserve, modified by genetic or acquired factors. Ovarian reserve tests, both biochemical and ultrasonografic, are realible markers of real ovarian reserve. Ovarian reserve markers are been used in statistic models to predict age at menopause, with important implications for women’s health and reproductive prognosis.


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12° Corso Strategie integrative, neuro-attive, e terapie ormonali in Ginecologia Endocrinologica
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