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Clomifene citrato o inibitori dell’aromatasi per l’induzione dell’ovulazione?


ABSTRACT
{ITA} L’Anovularietà Normogonadotropica, tra cui la sindrome dell’ovaio policistico (polycystic ovary syndrome, PCOS), è una delle principali cause di infertilità. Una recente meta-analisi ed uno studio randomizzato controllato suggeriscono l’uso di inibitori dell’aromatasi, ossia letrozole, come farmaco efficace e trattamento di prima linea per ripristinare la fertilità in queste pazienti.

{ENG} Normogonadotropic Anovulation, including polycystic ovary syndrome (PCOS), is a leading cause of infertility. A recent meta-analysis and a randomized controlled trial suggest the use of aromatase inhibitors, i.e. letrozole, as effective drug and first-line treatment to restore fertility in these patients.


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